Meiosis: SYP Up Firmly and Cross Over Evenly
نویسندگان
چکیده
منابع مشابه
Meiosis: SYP Up Firmly and Cross Over Evenly
The distribution and number of reciprocal DNA exchange events (crossovers) along meiotic chromosomes is tightly controlled. A recent report shows that unperturbed meiotic chromosome structure is important for this control, and that crossovers in turn modify chromosome structure locally.
متن کاملSYP-3 restricts synaptonemal complex assembly to bridge paired chromosome axes during meiosis in Caenorhabditis elegans.
Synaptonemal complex (SC) formation must be regulated to occur only between aligned pairs of homologous chromosomes, ultimately ensuring proper chromosome segregation in meiosis. Here we identify SYP-3, a coiled-coil protein that is required for assembly of the central region of the SC and for restricting its loading to occur only in an appropriate context, forming structures that bridge the ax...
متن کاملA Yeast Two-Hybrid Screen for SYP-3 Interactors Identifies SYP-4, a Component Required for Synaptonemal Complex Assembly and Chiasma Formation in Caenorhabditis elegans Meiosis
The proper assembly of the synaptonemal complex (SC) between homologs is critical to ensure accurate meiotic chromosome segregation. The SC is a meiotic tripartite structure present from yeast to humans, comprised of proteins assembled along the axes of the chromosomes and central region (CR) proteins that bridge the two chromosome axes. Here we identify SYP-4 as a novel structural component of...
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There are mutants of Salmonella enterica (with mutations in fliF and fliL) that shed flagella when they are swimming in a viscous medium or on the surface of soft agar. Filaments with hooks and the distal rod segment FlgG are recovered. We tried to extract flagellar filaments from such cells by pulling on them with an optical trap but failed, even when we used forces large enough to straighten ...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2014
ISSN: 0960-9822
DOI: 10.1016/j.cub.2013.11.007